Description
Uncompromising Quality Control
At Clear Peptides, quality is verified through independent third-party analytical testing conducted on each production batch. Every peptide is supplied with lot-specific Certificates of Analysis (COAs) confirming identity, purity, and batch consistency.
All materials undergo RP-HPLC purity analysis and ESI-MS identity confirmation before release. No lot ships without passing both tests.
Quality Comparison
| Feature / Testing Standard | Clear Peptides | Other Labs (Avg.) |
|---|---|---|
| Standard COA (Qualitative & Quantitative) | ✔ Included with every lot | ✘ Often incomplete |
| RP-HPLC Purity Analysis | ✔ Every batch, ≥98% criterion | ✘ Inconsistently performed |
| ESI-MS Identity Confirmation | ✔ Every batch | ✘ Rarely provided |
| Lot-Specific Documentation | ✔ Permanently archived, retrievable | ✘ Often unavailable |
| US-Based Fulfillment | ✔ FedEx 2-Day cold-chain | ✘ Variable |
MOTS-c — Research Overview
MOTS-c is a 16-amino acid mitochondrial-derived peptide (MDP) encoded within the 12S rRNA gene of the mitochondrial genome — representing a novel class of bioactive peptides with distinct mitochondria-to-nucleus signaling capabilities.
Research demonstrates that MOTS-c activates AMPK (AMP-activated protein kinase) and can translocate to the nucleus under metabolic stress conditions, where it interacts with gene regulatory elements associated with metabolic homeostasis — making it a unique research tool for inter-organelle communication studies.
Research Context Reported in Scientific Literature
MOTS-c has been evaluated in laboratory environments as described in peer-reviewed publications. Observations below are from controlled preclinical research models and do not constitute clinical evidence.
- AMPK activation pathway: AMP-activated protein kinase activation kinetics, substrate phosphorylation, and downstream metabolic signaling
- Mitochondrial retrograde signaling: Mitochondria-to-nucleus communication pathway investigation and nuclear translocation mechanism research
- Insulin sensitivity models: MOTS-c effects on insulin signaling pathway components in skeletal muscle cell models
- Folate cycle interaction: One-carbon metabolism pathway modulation and AICAR-mediated AMPK crosstalk research
- Exercise mimetic research: Investigation of MOTS-c as a pharmacological model for exercise-induced metabolic adaptation pathways
These observations are exploratory and not conclusive.
Format & Handling
Supplied in sterile laboratory glass vials containing lyophilized peptide material. Reconstitution with bacteriostatic water or an appropriate laboratory solvent is required prior to research use.
Handling and storage should follow institutional laboratory protocols to maintain stability, purity, and analytical integrity. Store sealed vials at −20°C, protected from light and moisture.
Frequently Asked Questions
🚚 How fast is shipping?
Orders placed before 2PM PST ship same day via FedEx 2-Day with cold-chain packaging. Most orders arrive within 2 business days.
📦 When will I receive my tracking number?
Tracking is emailed immediately upon dispatch, typically within 24 hours of order placement.
🧪 How do you verify purity and quality?
Every lot undergoes independent third-party RP-HPLC purity analysis and ESI-MS identity confirmation. Lot-specific COAs are available via our COA Lookup tool.
💳 What payment methods do you accept?
We accept major credit cards via our secure Bankful payment gateway. All transactions are encrypted and processed securely.
↩️ What is your refund policy?
All sales are final unless the issue results from a verified error or quality failure on our part. See our Refund Policy for full details.
❄️ How should I store this product?
Lyophilized powder should be stored at −20°C in a sealed, desiccated container protected from light. Avoid repeated temperature cycling. After reconstitution, store at 2–8°C and use within 72 hours.
Intended Use: Research use only. Not for human consumption, medical, veterinary, or diagnostic use. Research findings are preliminary and do not imply safety or efficacy.
